Patients with type 2 diabetes mellitus present similar immunological response to COVID-19 BNT162b2 mRNA vaccine to healthy subjects: a prospective cohort studyArticle Published on 2023-03-012023-07-10 Journal: Hormones (Athens, Greece) [Category] COVID19(2023년), [키워드] COVID-19 Diabetes Mellitus hyperglycemia immune response SARS-CoV-2 type 2 diabetes vaccination. [DOI] 10.1007/s42000-022-00405-7 PMC 바로가기
Impact of diabetes status and related factors on COVID-19-associated hospitalization: A nationwide retrospective cohort study of 116,370 adults with SARS-CoV-2 infectionArticle Published on 2022-12-012023-07-10 Journal: Diabetes research and clinical practice [Category] COVID19(2023년), [키워드] Comorbidities COVID-19 Hospitalization Type 1 diabetes type 2 diabetes vitamin D. [DOI] 10.1016/j.diabres.2022.110156 PMC 바로가기
Metabolic syndrome and aberrant immune responses to viral infection and vaccination: Insights from small animal modelsReview Published on 2022-11-302023-06-14 Journal: Frontiers in Immunology [Category] Fulltext, 신종인플루엔자, [키워드] dyslipidemia hypertension metabolic syndrome obesity type 2 diabetes vaccination vaccine efficacy Viral infection. [DOI] 10.3389/fimmu.2022.1015563 PMC 바로가기 [Article Type] Review
Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19Research article Published on 2022-11-012022-10-05 Journal: Bioorganic chemistry [Category] SARS, 신약개발, [키워드] activities activity addition Anti-inflammatory antioxidant Cell Co-receptor consequence COVID-19 CRP derivatives DPPH Effect evaluated IL-6 infections molecular docking not correlated novel OGT Patient Pyrimidinones question raised SARS-CoV-2 screened small molecule drug tested therapy Treatment type 2 diabete type 2 diabetes [DOI] 10.1016/j.bioorg.2022.106092 [Article Type] Research article
Comparing the B and T cell-mediated immune responses in patients with type 2 diabetes receiving mRNA or inactivated COVID-19 vaccinesArticle Published on 2022-10-112022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome adverse outcome Alpha Anti-RBD IgG BNT162b2 CD4 CD8 cell-mediated immune response cellular Clinical outcome comparable CoronaVac coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 vaccine COVID-19 vaccines diabete dose Effectiveness evaluated first dose healthy individual humoral immune response IgG antibody immune dysfunction Immunological memory immunological memory response Immunological response inactivated Infection influence initial memory mRNA neutralizing antibody neutralizing capacity of BNT162b2 Part Patient platform potential mechanism protective immunity RBD receiving Receptor binding domain reduction in resulting SARS-CoV2 second dose sera susceptibility T cell response T cells T2D Th1 titre Type type 2 diabete type 2 diabetes type 2 diabetes. vaccination vaccinee Vaccines [DOI] 10.3389/fimmu.2022.1018393 PMC 바로가기
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic systemArticle Published on 2022-09-212022-11-15 Journal: Cardiovascular Diabetology [Category] 바이오마커, 유전자 메커니즘, 진단, [키워드] absence addition analysed antibodies Anxiety Biomarker C-reactive protein cardiovascular disease Chronic fatigue circulation Clinicians Cognitive impairment Cohort Comorbidities Confusion contribute controls COVID COVID patient COVID-19 Depression detect disease Dyspnoea Evidence explain Failed fibrinolysis fatigue fibrinogen fibrinolytic system granular Health healthy controls Host immune response IL-6 implication increased risk individual Inflammatory inflammatory markers insoluble Kallikrein Long Long COVID mechanism Microclots PASC pathology Patient PF4 plasma Platelet platelet factor 4 platelet hyperactivation presence of antibody prevalent Prevent pro-inflammatory molecule Protein provided questionnaire reduced reported serum CRP sick Symptom thrombosis type 2 diabetes von Willebrand factor von Willebrand factor. vWF [DOI] 10.1186/s12933-022-01623-4 PMC 바로가기
COVID-19 induced Diabetes: A novel presentationReview article Published on 2022-09-012022-10-05 Journal: Diabetes research and clinical practice [Category] SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] affected assumed Atypical Beta cells biochemical biochemical pathway Case series cause caused Cell cell damage Complication COVID COVID-19 COVID-19 pandemic COVID-19 patient critically ill patients Cross-sectional studies detect diabete diabetes Diabetes Mellitus Diagnosis Diagnostic Criteria dysregulation Follow-up Glucose Google Scholar homeostasis implication include Infection insulin resistance management mechanisms meta-analyses Mortality mortality rate outcome parameter Pathogenesis pathophysiological mechanism Patient Prognosis Result risk factor SARS-CoV-2 significantly higher trajectory type 2 diabetes was performed [DOI] 10.1016/j.diabres.2022.110034 [Article Type] Review article
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19지방 조직에서의 ACE2 발현은 코로나19에 대한 심장 대사 위험 인자 및 세포 유형 구성과 관련이 있습니다.Meta-Analysis Published on 2022-08-012022-09-11 Journal: International journal of obesity (2005) [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] ACE2 ACE2 expression adipose Adipose tissue age angiotensin angiotensin I angiotensin I converting enzyme 2 BMI Cell cell type cell types cellular entry contribute COVID-19 COVID-19 severity diabetes Diseases distal Endothelial cell enzyme eQTLs expression Factor Factors fasting insulin feature Genetic HDL Health identify increased risk independent individual insulin investigated loci Lower lower expression Macrophage macrophages Meta-analysis obesity participant pathophysiology phenotypic proportion proximal Quantitative receptor risk risk factor RNA-Seq SARS-CoV-2 serum severe COVID-19 T2D tissue tissue expression type 2 diabete type 2 diabetes [DOI] 10.1038/s41366-022-01136-w PMC 바로가기 [Article Type] Meta-Analysis
Investigation of COVID-19 fear, treatment compliance, and metabolic control of patients with type 2 diabetes mellitus during the pandemicResearch article Published on 2022-08-012022-10-05 Journal: Primary care diabetes [Category] 치료법, [키워드] addition Affect age carried Compliance conducted COVID-19 COVID-19 pandemic criteria Data analysis duration of illness fear Fear of COVID-19 Follow-up form Helsinki Declaration hospital IBM identification implication investigation maintain mean score Metabolic control outpatient clinic pandemic Patient patients poor compliance Practice reduce Result scale single-center SPSS v25.0 the mean the patient Treatment Treatment compliance Turkey Type type 2 diabete type 2 diabetes type II diabete university hospital was used were used [DOI] 10.1016/j.pcd.2022.08.005 [Article Type] Research article
Vaccination coverage of patients with type 2 diabetes mellitus: Challenging issues from an outpatient secondary care setting in GreeceArticle Published on 2022-08-012023-06-01 Journal: Frontiers in Public Health [Category] 두창, 수두, 홍역, [키워드] infections prevention primary care type 2 diabetes vaccination. [DOI] 10.3389/fpubh.2022.921243 PMC 바로가기